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NAME

       ntdpal - Provides Primer3’s alignment functionality

SYNOPSIS

       ntdpal [-g gval] [-l lval] [-m mval] [-f1, f2, f3] [-p] [-s] [-e]
              {seq1} {seq2} {mode}

DESCRIPTION

       Ntdpal (NucleoTide Dynamic Programming ALignment) is a stand-alone
       program that provides Primer3´s alignment functionality (local, a.k.a.
       Smith-Waterman, global, a.k.a. Needleman-Wunsch, plus "half global").

OPTIONS

       -g gval
           gval is a (positive) float (.01 precision) specifying penaltiy for
           creating a gap respectively (the penalties are subtracted from the
           output score)

       -l val
           lval is a (positive) float (.01 precision) specifying penaltiy for
           lengthening a gap respectively (the penalties are subtracted from
           the output score)

       -a
           Causes the scoring matrix to be modified by
           dpal_set_ambiguity_codes.

       -e
           Causes the end postion of the alignment in both sequences to be
           printed. Do not confuse with the ´e´ mode.

       -f1, -f2, -f3
           Force specific implementations. -f2 forces use an implementation
           that might provide more informative error messages, possibly at the
           expense of some speed.

       -h
           Use a different scoring matrix: G and C matches = 3, A and T = 2,
           and mismatches = -0.5. (The default scoring matrix assigns 1 to a
           match, and -1 to a mismatch.)

       -p
           Causes the alignment to be displayed on stderr.

       -s
           causes only the score to printed.

       -m mval
           is the maximum allowed gap (default is 3).

       seq1 and seq2
           are the sequences to be aligned.

       mode
           is one of g, G, l, or L specifying a global, global end-anchored,
           local, or local end-achored alignment respectively. For backward
           compatibility e is equivalent to G.

REFERENCE

       Please cite Rozen, S., Skaletsky, H. "Primer3 on the WWW for general
       users and for biologist programmers." In S. Krawetz and S. Misener,
       eds. Bioinformatics Methods and Protocols in the series Methods in
       Molecular Biology. Humana Press, Totowa, NJ, 2000, pages 365-386.

SEE ALSO

       primer3_core(1) oligotm(1)

COPYRIGHT

       Copyright © 1996,1997,1998,1999,2000,2001,2004,2006,2007,2008 Whitehead
       Institute for Biomedical Research, Steve Rozen
       (http://jura.wi.mit.edu/rozen), Helen Skaletsky

       All rights reserved. On Debian-based systems, please consult
       /usr/share/doc/primer3/copyright to read the licence of ntdpal.

       This manual page was written by Charles Plessy <plessy@debian.org> for
       the Debian(TM) system (but may be used by others). Permission is
       granted to copy, distribute and/or modify this document under the same
       terms as oligotm itself.